Available by prescription only, amitriptyline hydrochloride (
Elavil®) is a medication used to treat
depression in adults and children over the age of 12. It belongs to a class of drugs known as
tricyclic antidepressants. These tablets come in six strengths (ranging from 10 mg to 150 mg), and amitriptyline can be taken with or without food.
With this medication, it is generally recommended to start at a low dose, which can be increased slowly if necessary. The recommended starting dosage of
amitriptyline for depression is 75 mg daily (divided into two or three smaller doses). Or instead of several doses a day, the starting dose can be 50 mg to 100 mg once a day at bedtime. For most people, the maximum total daily dosage of amitriptyline is 150 mg.
(To learn more about the 150-mg tablets, click Amitriptyline. This article offers more detailed dosing guidelines and explains how your healthcare provider will determine the right dosage for you.)