Medications
 
 

Amitriptyline Antidepressant

A commonly prescribed antidepressant is amitriptyline hydrochloride (Elavil®). It belongs to the class of drugs known as tricyclic antidepressants, and is believed to work by affecting the levels of certain chemicals in the brain, namely serotonin and norepinephrine. This product comes in tablet form and is typically taken one to three times daily. At this time, it is approved for use only in adults and children over the age of 12.
 
Although amitriptyline is an antidepressant, it may also be used "off-label" to help relieve chronic pain and to prevent migraine headaches. It can also help with bedwetting, ADHD, fibromyalgia, and bulimia. The medicine is also effective at helping people quit smoking.
 
Most people have no problems when taking this medication; however, side effects are possible. In clinical trials, commonly reported reactions included dizziness, drowsiness, constipation, and dry mouth.
 
(Click Amitriptyline to learn more about this medication, including general dosing information, what to do in cases of overdose, and important safety precautions.)
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD