The recommended starting amitriptyline dosage for the treatment of depression is 75 mg daily (divided into two or three smaller doses). Or instead of several doses a day, the starting amitriptyline dose can be 50 mg to 100 mg once a day at bedtime. It is generally recommended that amitriptyline be started at a low dose and increased slowly if necessary. Among the factors that can affect amitriptyline dosing are the medical condition being treated, other medical conditions you may have, and other drugs you may be taking.
An Overview of Amitriptyline DoingThe dose of amitriptyline hydrochloride (Elavil®) your healthcare provider prescribes will vary depending on a number of factors, including:
- Your age
- The medical condition being treated
- Other medical conditions you may have
- Other medications you may be currently taking.
As always, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
Amitriptyline Dosage for DepressionFor treating depression, the starting dose is amitriptyline 75 mg total daily (divided into two or three smaller doses). Or instead of several doses a day, the starting dose can be amitriptyline 50 mg to 100 mg once a day at bedtime. The dose can be increased slowly if necessary. A starting dose of up to 100 mg is acceptable for people who are in the hospital.
For teenage depression or depression in the elderly, lower doses are recommended. A good starting dose for these people is 10 mg three times daily, or 25 mg once a day at bedtime.
Generally, amitriptyline should be started at a low dose (especially in the elderly) and increased slowly if necessary. The maximum dose for most people is 150 mg total daily. People who are in the hospital can take up to 300 mg per day.