Amitriptyline Overdose: An Overview
Amitriptyline hydrochloride (
Elavil®) is a prescription medication that has been licensed to treat
depression. It is one of a group of medications called
tricyclic antidepressants. As with all medicines, it is possible to take too much amitriptyline. An overdose with tricyclic
antidepressants can be very dangerous. The effects of an Elavil overdose (amitriptyline overdose) will vary depending on a number of factors, including how much amitriptyline was taken and whether it was taken with any other medicines, alcohol, and/or drugs.
If you happen to overdose on amitriptyline, seek medical attention immediately.
Symptoms of an Amitriptyline Overdose
The effects of an amitriptyline overdose may include:
- Changes in heart rhythm (arrhythmia)
- Very low blood pressure (hypotension)
- Seizures
- Sleepiness or fainting
- Confusion
- Restlessness
- Seeing things that are not really there (hallucinations)
- Dilated (wide open) pupils
- Agitation
- Vomiting
- Fever
- Loss of life.
Treatment for an Amitriptyline Overdose
The treatment for an amitriptyline overdose will vary.
If the amitriptyline overdose was recent, the healthcare provider may use certain medicines or place a tube into the stomach to "pump the stomach." Treatment may also involve supportive care. This type of care consists of treating the symptoms that occur as a result of the overdose. For example, supportive treatment options for an amitriptyline overdose may include:
- Fluids through an intravenous line (IV)
- Medicines to increase blood pressure, control an irregular heart rhythm, or control seizures
- Closely monitoring the heart and lungs
- A breathing tube to help with breathing
- Other treatments based on the complications that occur.
If you began treatment with amitriptyline and overdosed, and/or believe you may have overdosed, seek medical attention immediately.
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