Medications
 
 

Amitriptyline Safety

If you have depression, your healthcare provider may recommend the prescription drug amitriptyline hydrochloride (Elavil®) to help improve your symptoms.
 
Most people respond well to this antidepressant. However, before you begin treatment with amitriptyline, safety issues regarding the medication should be reviewed with your healthcare provider. For example, it is important to know that all antidepressants can increase the risk of suicidal thoughts or behavior; you should seek medical attention if you experience anxiety, hostility, or panic while taking this drug.
 
It is also possible to develop side effects while taking amitriptyline. Some of the most common problems that have been reported include dizziness, drowsiness, confusion, and constipation. In addition, some people may not be able to take the drug safely, such as those with certain allergies or who have recently had a heart attack.
 
(For more safety information, click Amitriptyline Side Effects and Amitriptyline Warnings and Precautions. These articles take an in-depth look at other side effects or complications that may occur with the use of this medication.)
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD