Medications
 
 

Amitriptyline Substitute

Amitriptyline hydrochloride (Elavil®) is a prescription drug commonly used to relieve symptoms of depression. It also can be used in an off-label fashion to treat various anxiety disorders. Most people have no problems when taking this medication, but sometimes bothersome side effects occur or it may not work as well as you and your healthcare provider hoped. In such cases, a substitute for amitriptyline can be considered.
 
Alternatives to amitriptyline can include other antidepressants or anti-anxiety medications, as well as "talk" therapies, such as cognitive behavioral therapy. In fact, talk therapies are often used in conjunction with medications to treat conditions like depression.
 
(Click Anxiety Medications to learn more about the various amitriptyline substitutes available, including the different classes and how they work, and who can prescribe these medicines.)
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD