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Antidepressant Uses

Antidepressants are most commonly used for treating depression. However, these medications can also be used for other conditions as well. For example, newer antidepressants (such as SSRIs, SNRIs, and NDRIs) have been approved for treating conditions such as panic disorder, bulimia, and social anxiety disorder. General off-label antidepressant uses include the treatment of Tourette syndrome, autism, migraines, and premature ejaculation.

 

Uses of Antidepressant: An Overview

As would be expected, the most common use for most antidepressants is depression treatment. However, most antidepressants are approved for treating other conditions as well. These uses vary with the different types of antidepressants.
 

SSRI, SNRI, or NDRI Antidepressant Uses

Various
 SSRIs (selective serotonin reuptake inhibitors) have been approved for the following uses:
 
Not all SSRIs are approved for all of the above uses (see Comparisons of SSRI Antidepressants for more information).
 
Various SNRIs (serotonin-norepinephrine reuptake inhibitors) are approved for the following uses:
 
Not all SNRIs are approved for all of the above uses.
 
NDRIs (norepinephrine and dopamine reuptake inhibitors) have been approved to treat depression and for use as a smoking cessation agent (to help people stop smoking). Currently, there is only one NDRI medication, bupropion (Wellbutrin®, Wellbutrin SR®, Wellbutrin XL®, Zyban®), approved for this use in the United States.
 
(Antidepressant Uses Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;