Aplenzin Drug Interactions

When alcohol, antipsychotic medications, or beta blockers are taken with Aplenzin, drug interactions may occur. These interactions can alter the level of Aplenzin in your blood and increase your risk of serious side effects. To avoid any complications, your healthcare provider may need to monitor you more closely or adjust your dosage of the medications.

Aplenzin Medication Information

An Overview of Interactions With Aplenzin

Aplenzin™ (bupropion hydrobromide) can potentially interact with a number of other medications. Some of the medicines that may lead to drug interactions with Aplenzin include but are not limited to:

Alcohol
Other antidepressants
Amantadine (Symmetrel^®)
Antipsychotic medications (used to treat hallucinations or schizophrenia)
Beta blockers, such as:
- Atenolol (Tenormin^®)
- Bisoprolol (Zebeta^®)
- Carvedilol (Coreg^®, Coreg CR^®)
- Labetalol (Trandate^®)
- Metoprolol (Lopressor^®, Toprol-XL^®)
- Nadolol (Corgard^®)
- Propranolol (Inderal^®)
- Sotalol (Betapace^®)
- Timolol (Blocadren)

Certain arrhythmia medications, including propafenone (Rythmol^®) and flecainide (Tambocor^®)
Clopidogrel (Plavix^®)
Cyclophosphamide (Cytoxan^®)
Doxorubicin (Adriamycin^®, Doxil^®)
Efavirenz (Sustiva^®)
Levodopa medications, such as Sinemet^®, Sinemet^® CR, Parcopa^®, or Stalevo^®
Monoamine oxidase inhibitors (MAOIs), including:
- Isocarboxazid (Marplan^®)
- Phenelzine (Nardil^®)
- Rasagiline (Azilect^®)
- Selegiline (Eldepryl^®, Emsam^®, Zelapar^®)
- Tranylcypromine (Parnate^®)

Nelfinavir (Viracept^®)
Nicotine patches (such as NicoDerm CQ^®)
Orphenadrine (Norflex^®)
Ritonavir (Norvir^®) or lopinavir and ritonavir (Kaletra^®)
Tamoxifen (Nolvadex^®)
Steroids, such as prednisone or methylprednisolone (Medrol^®)
Theophylline (Uniphyl^®, Theochron^®, TheoCap^®, Theo-24^®, Elixophyllin^®)
Thiotepa
Ticlopidine (Ticlid^®).

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