Beta Blockers
Budeprion XL may increase the level of
beta blockers in your blood, possibly increasing your risk of side effects. Your healthcare provider may need to monitor you more closely and may need to decrease your dose of beta blockers to prevent this interaction from occurring.
Certain Arrhythmia Medications
Budeprion XL may increase the level of certain arrhythmia medications in your blood, increasing your risk of side effects. To prevent this, your healthcare provider may need to monitor you more closely, especially when starting or stopping Budeprion XL.
Clopidogrel
Clopidogrel may slow the metabolism of Budeprion XL in the body, potentially leading to high levels of Budeprion XL and a potentially higher risk of Budeprion XL side effects. Check with your healthcare provider before taking these medications together.
Cyclophosphamide
Cyclophosphamide may interact with Budeprion XL, although there have been no reports of such an interaction in actual patients. Depending on your situation, your healthcare provider may need to monitor you more closely and may need to adjust your dose of these medications.
Doxorubicin
Doxorubicin may increase the level of Budeprion XL in your blood, increasing your chance of side effects. Your healthcare provider may need to decrease your Budeprion XL dose while you are taking doxorubicin.
Efavirenz
Efavirenz may increase the metabolism of Budeprion XL, leading to decreased levels of Budeprion XL in the blood, and possibly to decreased effectiveness. Check with your healthcare provider before taking such medications together. You may need a higher Budeprion XL dosage, although the maximum recommended dosage should not be exceeded, even if you are taking efavirenz.