Celexa Drug Interactions

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Taking Celexa and NSAIDs together can increase your risk of stomach bleeding. Talk to your healthcare provider before taking NSAIDs and Celexa together.
 
Pimozide (Orap)
Pimozide and Celexa should not be taken together, as the combination may cause a dangerous irregular heart rhythm (arrhythmia) called QT prolongation. Do not take these two medications together.
 
SSRI or SNRI Antidepressants
Taking Celexa with other SSRI or SNRI antidepressants can cause a group of symptoms called serotonin syndrome. Talk to your healthcare provider before taking these depression medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome (see above), as it can be very dangerous.
 
St. John's Wort
Taking Celexa with St. John's wort can cause a group of symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome (see above), as it can be very dangerous.
 
Tramadol (Rybix ODT, Ryzolt, Ultram, Ultram ER) or Tramadol and Acetaminophen (Ultracet)
Taking Celexa with a tramadol can cause a group of symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome (see above), as it can be very dangerous.
 
Tricyclic Antidepressants
Taking Celexa with tricyclic antidepressants can increase the level of tricyclic antidepressants in your blood. Your healthcare provider may need to reduce your dose of the tricyclic antidepressant.
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Celexa Drug Information

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