How Does Celexa Work?

Celexa® (citalopram hydrobromide) is a medication approved for the treatment of depression. It is available by prescription only and comes in both tablet and liquid form.
So how does Celexa work? It is part of a class of drugs called selective serotonin reuptake inhibitors. The medication acts on a specific chemical within the brain known as serotonin, one of several chemicals used to send messages from one nerve cell to another.
As a message travels down a nerve, it causes the end of the cell to release serotonin. The serotonin enters the gap between the first nerve cell and the one next to it. When enough serotonin reaches the second nerve cell, it activates receptors on the cell and the message continues on its way. The first cell then quickly absorbs any serotonin that remains in the gap between cells. This is called "reuptake."
Normally, this process works without any problems. When the levels of serotonin become unbalanced, however, it can cause a variety of conditions, including depression. Celexa works by blocking the reuptake of serotonin so more remains in the space between the brain's nerve cells. This gives the serotonin a better chance of activating the receptors on the next nerve cell.
(Click Celexa for more information on how Celexa works, to learn about the drug's effects, and to find out what side effects may occur with this medication.)
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