Cymbalta® (duloxetine hydrochloride) is a prescription medicine licensed to treat generalized anxiety disorder, fibromyalgia, chronic pain, and peripheral diabetic neuropathy pain. People with depression can also benefit from Cymbalta.
When the levels of certain brain chemicals (serotonin and norepinephrine) become unbalanced, it can cause a variety of conditions, including depression or anxiety. Cymbalta works by blocking the reuptake of serotonin and norepinephrine, which can help re-balance these chemical levels.
Although it is not entirely clear how Cymbalta works for nerve pain, the drug appears to help block the pain signals in the spinal cord or brain. This may help relieve the pain of peripheral diabetic neuropathy. It is not clear how exactly Cymbalta works for fibromyalgia pain.
Some of the most common side effects that have been reported with this antidepressant include dry mouth, constipation, and drowsiness. Cymbalta comes in capsule form and is typically taken once or twice a day.
(Click Cymbalta for more information about this medication, to find out when and how to take it, and to learn about potential side effects.)