Medications
 
 

Cymbalta Drug Interactions

Quinidine
Taking Cymbalta with quinidine can increase the level of Cymbalta in your blood, increasing your risk of side effects. Your healthcare provider may need to decrease your Cymbalta dose.
 
Quinine
Taking Cymbalta with quinine can increase the level of Cymbalta in your blood, increasing your risk of side effects. Your healthcare provider may need to decrease your Cymbalta dose.
 
Ritonavir (Norvir)
Taking Cymbalta with ritonavir can increase the level of Cymbalta in your blood, increasing your risk of side effects. Your healthcare provider may need to decrease your Cymbalta dose.
 
Ropinirole (Requip)
Taking Cymbalta with ropinirole can increase the level of Cymbalta in your blood, increasing your risk of side effects. Your healthcare provider may need to decrease your Cymbalta dose.
 
SSRI or SNRI Antidepressants
Taking Cymbalta with other SSRI or SNRI antidepressants can cause a group of symptoms called serotonin syndrome. Talk to your healthcare provider before taking these depression medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome (see above), as it can be very dangerous.
 
St. John's Wort
Taking Cymbalta with St. John's wort can cause a group of symptoms called serotonin syndrome. Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome (see above), as it can be very dangerous.
 
Terbinafine (Lamisil)
Taking Cymbalta with terbinafine can increase the level of Cymbalta in your blood, increasing your risk of side effects. Your healthcare provider may need to decrease your Cymbalta dose.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
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