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Cymbalta for Depression

Cymbalta® (
 duloxetine hydrochloride) is a prescription medication used to treat several conditions, including depression. In studies, people taking Cymbalta for depression had more improvement in their symptoms, compared to those not taking it.
 
Cymbalta is part of a class of drugs called serotonin-norepinephrine reuptake inhibitors, or SNRIs for short. It helps to block the reuptake of serotonin and norepinephrine (specific chemicals in the brain) so that more remains in the space between the brain's nerve cells. This gives the chemicals a better chance of activating the receptors on the next nerve cell. As a result, the levels of these chemicals in the brain are more balanced and symptoms of depression can be alleviated.
 
(Click Cymbalta for a more in-depth look at using Cymbalta for depression and other conditions, such as anxiety and fibromyalgia. This article also discusses how the medication works and offers information on general precautions, dosages, and potential side effects.)
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;