Medications
 
 

Cymbalta

Effects of Cymbalta

Several studies have looked at the effects of Cymbalta on a variety of conditions.
 
Depression
Four studies have shown Cymbalta to be effective for depression treatment in adults. In these studies, people taking the drug had more improvement in their depression symptoms, compared to those not taking it.
 
Neuropathy
Cymbalta has also been studied for neuropathic pain (nerve pain) in people with peripheral diabetic neuropathy. These studies included people with either type 1 or type 2 diabetes who had been experiencing diabetic neuropathy pain for at least six months. People taking the drug were more likely to have half as much pain as before, compared to those not taking it.
 
Anxiety
Studies have also shown Cymbalta to be effective for treating generalized anxiety disorder (GAD). People taking it had greater improvements in their anxiety symptoms, compared to those who were not.
 
Fibromyalgia
Studies indicate that Cymbalta can help reduce fibromyalgia pain. Cymbalta was more effective than a placebo (a "sugar pill") for relieving pain, even in people who did not have depression along with fibromyalgia (although it was most effective in people that had depression).
 
Musculoskeletal Pain
Studies have shown Cymbalta to be effective for treating chronic back pain and chronic osteoarthritis pain. In general, people taking Cymbalta experienced more pain relief, compared to those taking a placebo, although not all studies were favorable.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
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