There are no generic Deplin products available, as this vitamin is considered a "medical food," rather than a prescription medication. Because it is a medical food, Deplin does not have to be approved by the U.S. Food and Drug Administration. However, there are other products available that contain L-methylfolate, the active form of folic acid that is in Deplin.
Deplin® is a medical food used to help manage low folate levels in people with depression. It may also be used in people who have schizophrenia and high homocysteine blood levels (hyperhomocysteinemia). Deplin should only be used with a healthcare provider's supervision.
Deplin is made by Pamlab, LLC. Because it is a medical food, there are no generic versions of it.
All generic medications must undergo certain tests to compare them to brand-name medications. The U.S. Food and Drug Administration (FDA) then looks at these tests to decide if the generics are equivalent to the brand-name medications and assigns each generic a rating.
However, Deplin is considered a medical food, not a prescription medication. Medical foods are used to provide nutritional supplementation for medical conditions that have specific nutritional needs. They do not need to be approved by the FDA. Therefore, no testing is done to determine if products are equivalent. This means that, technically, there are no brand-name or generic versions of medical foods.
Deplin contains L-methylfolate, which is the active form of folic acid. There are other supplements available that contain L-methylfolate. However, as mentioned above, there is no way to determine if these products are equivalent to Deplin.
When you take folic acid, the body converts it to L-methylfolate, which is the active form of the vitamin. Some people may wonder if taking folic acid will provide the same effects as Deplin. Although it is possible, you would have to take many folic acid tablets to equal one Deplin tablet (because the body will convert the folic acid into L-methylfolate). In addition, some people are unable to convert folic acid to L-methylfolate. For these people, taking L-methylfolate may be the best option.
If you are looking for an alternative to Deplin, for financial or other reasons, talk to your healthcare provider. He or she will take your individual situation into consideration and recommend an alternative product, if one is available, for your particular treatment needs.