Sold under the brand name Norpramin®, desipramine hydrochloride (HCl) is a prescription medicine that is licensed for depression treatment in adults. It is also used occasionally "off-label" for the treatment of fibromyalgia, chronic pain, anxiety disorder, and many other conditions. Available in tablet form, this tricyclic antidepressant works by affecting certain chemicals in the brain (serotonin and norepinephrine).
As with any medication, side effects are possible with desipramine. Commonly reported reactions to this drug include dry mouth, constipation, and drowsiness. In general, however, it is well tolerated.
(Click Desipramine for more details, including tips on when and how to take it, what to do if you miss a dose, and more.)