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Depression? Major depresion is a common misspelling and variation of depression.
Despite what people may think, depression is not a passing phase or something that can be willed away. Major depression is an illness affecting a person's body, mood, and thoughts. Common symptoms include irritability, feelings of guilt and helplessness, and persistent physical symptoms that do not respond to treatment. Major depression is often treated with medications, psychotherapy, or a combination of the two.
(Click Depression to read the complete eMedTV article, which explains in detail who depression tends to affect, how it is diagnosed, coping mechanisms, and more.)