Fortunately, there are many medications available to treat depression. These medications can include:
- Selective serotonin reuptake inhibitors (SSRIs)
- Serotonin-norepinephrine reuptake inhibitors (SNRIs)
- Monoamine oxidase inhibitors (MAOIs)
- Other tricyclic antidepressants
- Miscellaneous other antidepressants.
Selective Serotonin Reuptake Inhibitors (SSRIs)
Generally, SSRIs are very effective at treating depression and do not have many serious side effects. They work by increasing the level of serotonin available for cells of the brain. Some examples of SSRIs include:
- Citalopram (Celexa®)
- Escitalopram (Lexapro®)
- Fluoxetine (Prozac®, Sarafem®, Selfemra™)
- Fluvoxamine (Luvox®, Luvox CR)
- Paroxetine (Paxil®, Paxil CR®, Pexeva®, Brisdelle™)
- Sertraline (Zoloft®).
Serotonin-Norepinephrine Reuptake Inhibitors
These antidepressants are very similar to SSRIs, except that they also affect norepinephrine (another chemical in the brain). Among the SNRIs used to treat depression are:
- Desvenlafaxine (Pristiq™)
- Duloxetine (Cymbalta®)
- Levomilnacipran (Fetzima™)
- Venlafaxine (Effexor®, Effexor XR®).
Milnacipran (Savella™) is an SNRI that is not approved for the treatment of depression (although it may be used off-label for this purpose).