Medications
 
 

Desipramine Alternatives

Other Depression Medications

Fortunately, there are many medications available to treat depression. These medications can include:
 
Selective Serotonin Reuptake Inhibitors (SSRIs)
Generally, SSRIs are very effective at treating depression and do not have many serious side effects. They work by increasing the level of serotonin available for cells of the brain. Some examples of SSRIs include:
 
Serotonin-Norepinephrine Reuptake Inhibitors
These antidepressants are very similar to SSRIs, except that they also affect norepinephrine (another chemical in the brain). Among the SNRIs used to treat depression are:
 
Milnacipran (Savella™) is an SNRI that is not approved for the treatment of depression (although it may be used off-label for this purpose). 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
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