When medications, therapy, and the combination of these treatments prove ineffective, or work too slowly to relieve severe symptoms, electroconvulsive therapy (ECT) may be considered.
Some people may also consider complementary or alternative treatments for depression. Complementary or alternative treatments may include:
- St. John's wort
- Omega-3 fatty acids
- Vitamin B6
- SAMe (S-adenosyl-L-methionine)
- 5-HTP (5-hydroxytryptophan)
(Click Natural Remedies for Depression or Acupuncture and Depression for more information on what research has shown regarding these alternative treatments.)
There are several desipramine alternatives, including other medications and therapy. Talk with your healthcare provider if desipramine is not working for you or your child, or if you are experiencing bothersome desipramine side effects. You may need to try one of the other depression treatments.