Depression, even in its most severe form, is highly treatable. As with many illnesses, getting
depression treatment early is more effective and reduces the chance of recurrence.
The most common forms of depression treatment are medication (
antidepressants) and psychotherapy ("talk therapy"). In some cases of severe depression, healthcare providers may recommend electroconvulsive therapy (ECT). Some people may also try complementary or alternative treatments for depression
(see Natural Remedies for Depression).
For most people, desipramine is quite effective at treating depression. It is also generally well tolerated. However, it is possible that side effects will occur or that the medicine may not work as well as needed. In these cases, your healthcare provider may recommend an alternative to desipramine. Some examples of substitute depression medications include: