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Desipramine Side Effects (Cont.)

Desipramine Side Effects to Report

There are a number of less common but more serious side effects with desipramine that you should report to your healthcare provider. Some of these side effects include:
 
  • A heart attack or stroke
  • Changes in heart rhythm (arrhythmia)
  • A fast heart rate (tachycardia) or feelings of a rapidly or forcefully beating heart (palpitations)
  • Seizures
  • Confusion, delusions, or hallucinations
  • Signs of an allergic reaction, including unexplained rash, hives, itching, unexplained swelling, wheezing, or difficulty breathing or swallowing
  • Any breast changes, including breast enlargement or breast discharge
  • Swelling of the testicles
  • Yellowing of the eyes or skin (jaundice)
  • Suicidal thoughts or behavior (see Desipramine and Suicide)
  • Hostility or aggressiveness
  • Engaging in unusual or dangerous activities
  • Restlessness or an inability to sit still
  • Extreme elation or feelings of happiness that may switch back and forth with a depressed or sad mood
  • Other unusual changes in behavior
  • Difficulty sleeping
  • Anxiety, agitation, or panic attacks.
     

Desipramine Side Effects: Summary

You may experience some or none of the desipramine side effects explained above. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have side effects from a medicine that you have never tried. Therefore, be sure to let your healthcare provider know if you develop any side effects, or something that "just does not seem right," while taking desipramine. While it may not be a desipramine side effect, your healthcare provider will be able to diagnose and treat the problem.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;