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Desipramine Side Effects

Dry mouth, a loss of appetite, and constipation are some of the more common side effects that have been reported with desipramine. Side effects for the most part are minor and can easily be treated by you or your healthcare provider. However, it is possible to develop more serious side effects, such as changes in heart rhythm, jaundice, or panic attacks. Be sure to notify your healthcare provider if you develop any serious side effects with desipramine.

 

Desipramine Side Effects: An Introduction

As with any medicine, there are possible side effects with desipramine hydrochloride (Norpramin®). However, not everyone who takes the medicine will experience side effects. In fact, most people tolerate the drug well. When people do develop desipramine side effects, in many cases they are minor, meaning they require no treatment or are easily treated by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with desipramine. Your healthcare provider can discuss a more complete list of desipramine side effects with you.)
 

Side Effects of Desipramine

Desipramine has been studied thoroughly in clinical trials. In these studies, the side effects that occur in a group of people taking the drug are documented and are then compared to side effects that occur in another group of people not taking the medicine. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.
 
In these studies, some of the side effects of desipramine included:
 
Some additional side effects that may be expected (based on how desipramine works) include:
 
  • Dizziness
  • Lightheadedness
  • Drowsiness.
     
Withdrawal side effects have been reported in people who have stopped taking desipramine suddenly. These side effects of desipramine withdrawal can include nausea, headaches, and a general ill feeling (see Desipramine Withdrawal).
 
(Desipramine Side Effects Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;