Precautions and Warnings With Desipramine

Some precautions and warnings with desipramine include possible drug interactions, the safety of taking desipramine while pregnant, and the risk of withdrawal symptoms or a dry mouth in some people taking this medicine. Among the people who should not take desipramine are those who have recently had a heart attack and those who are taking monoamine oxidase inhibitors (MAOIs). A few of the conditions that you should let your healthcare provider know about before you take desipramine include glaucoma, seizures, and heart problems (including heart disease).

Desipramine HCl

Desipramine: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking

desipramine hydrochloride (Norpramin^®) if you have:

Bipolar disorder (manic depression) or a family history of bipolar disorder
Schizophrenia
A history of suicide attempts or suicidal thoughts
Severe anxiety or agitation
A recent history of a heart attack
Heart problems, including heart disease
Hyperthyroidism (overactive thyroid)
Seizures
Glaucoma
Bladder problems or difficulty passing urine
An enlarged prostate (also known as benign prostatic hyperplasia or BPH)
Any allergies, including allergies to foods, dyes, or preservatives.

Also let your healthcare provider know if you:

Are pregnant or thinking of becoming pregnant
Are breastfeeding
Drink alcohol regularly.

You should also make sure to tell your healthcare provider about all other medicines you may be taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

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