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Emsam and Weight Loss

In previous clinical studies, up to 5 percent of people taking Emsam experienced a weight loss of at least 5 percent of their body weight. Although the actual connection between Emsam and weight loss is unclear, it is believed that weight loss may occur because the antidepressant has been known to cause a loss of appetite, diarrhea, and vomiting. Because unintended weight loss can be a problem for a lot of people, be sure to notify your healthcare provider if you lose too much weight while taking Emsam.

 

An Overview of Emsam and Weight Loss

Emsam® (selegiline transdermal patch) is a prescription medicine used for the treatment of depression (also known as major depression or clinical depression). There are a number of possible side effects of Emsam. Weight loss appears to be one of them. For some people, this may be a good thing. For a lot of people, however, unintended weight loss can be a problem.
 

How Common Is Weight Loss With Emsam?

In previous clinical studies, up to 5 percent of people taking Emsam experienced a weight loss of at least 5 percent of their body weight, compared to 2.8 percent of those people not taking Emsam. On average, though, people lost only 1.2 pounds while taking Emsam. However, it is possible for people to lose large amounts of weight while taking Emsam.
 

Why Does Emsam Cause Weight Loss?

It is not entirely clear why Emsam causes weight loss. Emsam can often cause a loss of appetite, vomiting, and diarrhea -- all of which may contribute to weight loss. Often, these side effects go away with time. Also, since weight gain can be a symptom of depression, treating the depression can lead to weight loss.
 
If you are experiencing too much weight loss with Emsam, be sure to let your healthcare provider know.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;