Emsam Drug Interactions

Cyclobenzaprine (Flexeril)
Due to the risk of dangerous side effects (such as high blood pressure or seizures), you should not take cyclobenzaprine and Emsam within two weeks of each other. 
 
Meperidine (Demerol)
You should not take meperidine while taking Emsam (or if you have taken Emsam within the past 14 days) due to the risk of dangerous side effects.
 
Methadone (Dolophine, Methadose)
You should not take methadone while taking Emsam (or if you have taken Emsam within the past 14 days) due to the risk of dangerous side effects.
 
Miscellaneous Antidepressants
You should not take certain antidepressants while taking Emsam (or if you have taken Emsam within the past 14 days) due to the risk of dangerous side effects.
 
Monoamine Oxidase Inhibitors (MAOIs)
Taking Emsam with other MAOIs can increase your chances of developing dangerous side effects. Do not take Emsam and other MAOIs within two weeks of each other.
 
Oxcarbazepine (Trileptal)
You should not take oxcarbazepine while taking Emsam (or if you have taken Emsam within the past 14 days) due to the risk of dangerous side effects.
 
Propoxyphene (Darvon, Darvocet, Balacet)
You should not take propoxyphene while taking Emsam (or if you have taken Emsam within the past 14 days) due to the risk of dangerous side effects.
 
Pressors
Due to the risk of dangerous side effects (such as high blood pressure), you should not take pressors and Emsam within two weeks of each other.
 
Sibutramine (Meridia)
You should not take sibutramine and Emsam within 14 days of each other due to the risk of dangerous side effects.
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