Emsam Side Effects

Side Effects to Report

There are a number of Emsam side effects that you should report to your healthcare provider. These include but are not limited to:
  • Dangerously high blood pressure (called a hypertensive crisis). Signs of a hypertensive crisis can include:


    • Headaches
    • Feelings of a rapidly or forcefully beating heart (palpitations)
    • A sore or stiff neck
    • Nausea or vomiting
    • Sweating, with a high fever (or sometimes with cold, clammy skin)
    • Sensitivity to light
    • A rapid heart rate (tachycardia) or slow heart rate (bradycardia)
    • Chest pain or throat tightness
    • Dilated (wide open) pupils.


  • Low blood pressure (hypotension). Signs of low blood pressure can include:


    • Dizziness
    • Lightheadedness
    • Fainting.


  • Confusion, delusions, or hallucinations
  • Suicidal thoughts or behavior (see Emsam and Suicide)
  • Hostility or aggressiveness
  • Engaging in unusual or dangerous activities
  • Restlessness or an inability to sit still
  • Extreme elation or feelings of happiness that may switch back and forth with a depressed or sad mood
  • Other unusual changes in behavior
  • Anxiety, agitation, or panic attacks
  • Signs of an allergic reaction, including an unexplained rash, hives, itching, unexplained swelling, wheezing, or difficulty breathing or swallowing.
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