Clinical Effects of Fetzima

Fetzima has been studied in three clinical studies that included people with major depressive disorder between the ages of 18 and 78 years old. In these studies, people were randomly assigned to receive either Fetzima or a placebo (a "sugar pill" with no active ingredients). In all three studies, people taking Fetzima had a greater improvement in their depressive symptoms after eight weeks of treatment compared to those taking the placebo.

When and How to Take It

Some general considerations to keep in mind during treatment with Fetzima include the following:
  • Fetzima comes in the form of a capsule. It is usually taken by mouth once a day.
  • You can take your dose with or without food. Try taking it with food if it upsets your stomach.
  • This medication can be taken any time during the day. If it makes you drowsy, try taking it at night. If it causes insomnia, take it in the morning.
  • You should take your dose at the same time each day to keep an even level of the drug in your bloodstream.
  • Fetzima should be swallowed whole. Do not cut, crush, or chew the capsules.
  • Suddenly stopping medications like Fetzima can cause uncomfortable withdrawal-type symptoms (see Fetzima Withdrawal). If you need to stop taking this medication, your healthcare provider will likely slowly reduce your dose.
  • For the medication to work properly, it must be taken as prescribed. Fetzima will not work if you stop taking it.  

Dosing Information

The dose of Fetzima your healthcare provider recommends will vary, depending on a number of factors, including:
  • How you respond to this medication
  • Other drugs you are taking
  • Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
(Click Fetzima Dosage for more information.)
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Fetzima Medication Information

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