Forfivo XL Warnings and Precautions

You may have an increased risk for weight loss, liver damage, or suicidal thoughts during treatment with Forfivo XL. Other safety precautions with this antidepressant involve understanding the warnings of potential drug interactions and allergic reactions. Also, women who are pregnant or breastfeeding should talk to their healthcare provider before beginning treatment.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Forfivo™ XL (bupropion XL) if you have:
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings With Forfivo XL

Some warnings and precautions to be aware of prior to taking this medication include the following:
    • Seizure disorders
    • Bulimia or anorexia
    • Brain trauma or brain injury
    • Severe liver cirrhosis.
Also, people taking certain medications have a higher risk for seizures (see Forfivo XL Drug Interactions). Abruptly stopping alcohol or sedative medications can also increase your chance of this complication.
  • Antidepressants, including Forfivo XL, may increase the risk for suicidal thoughts or behavior in children, teenagers, and adults (see Depression and Suicide for more information). Therefore, if you notice any changes in symptoms or new symptoms, talk to your healthcare provider immediately (see Antidepressants and Suicide for more information).
Some of these symptoms may include:
    • Anxiety
    • Hostility
    • Agitation
    • Panic
    • Restlessness
    • Hallucinations
    • Extreme hyperactivity
    • Suicidal thoughts or behavior.
  • Before prescribing Forfivo XL for depression, your healthcare provider should make sure you do not have bipolar disorder. Sometimes, the symptoms of bipolar disorder and depression are quite similar, and Forfivo XL can cause problems in people with bipolar disorder.
  • Forfivo XL should not be used right after a heart attack. Also, there is some evidence that this antidepressant can cause irregular heart rhythms (arrhythmias) in people with heart disease.
  • This drug can cause liver damage. Also, because the liver and kidneys help to remove Forfivo XL from the blood, you should talk to your healthcare provider before taking this antidepressant if you have liver or kidney problems.
  • This medication can cause mental problems, especially in people who are just starting treatment with it. Tell your healthcare provider if you are experiencing any of signs of these problems, such as:
    • Insomnia
    • Agitation
    • Hallucinations
    • Confusion.
  • Forfivo XL can cause weight loss. This can be a problem for some people, especially those who are underweight (see Forfivo XL and Weight Loss for more information).
  • Forfivo XL can cause allergic reactions. Tell your healthcare provider if you have signs of an allergic reaction, such as:
    • An unexplained skin rash
    • Itching
    • Hives
    • Trouble breathing
    • Unexplained swelling.
  • Sometimes, this drug can cause high blood pressure (hypertension), especially in people using nicotine patches. Your healthcare provider should monitor your blood pressure if you are taking Forfivo XL. It is unknown whether it would cause problems in people who have heart disease or who have recently had a heart attack.
  • Forfivo XL is a pregnancy Category C medication. This means that it may not be safe to take during pregnancy. Talk to your healthcare provider about the risks and benefits of using this antidepressant while pregnant (see Forfivo XL and Pregnancy for more information).
  • Forfivo XL passes through breast milk. Therefore, if you are breastfeeding or plan to start, talk with your healthcare provider before using this medication (see Forfivo XL and Breastfeeding).
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Forfivo XL Medication Information

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