Drug Interactions With Imipramine Pamoate

St. John's Wort
Combining imipramine pamoate with St. John's wort may increase the risk of serotonin syndrome. Check with your healthcare provider before taking these medications together.
  
Thyroid Medications
Taking imipramine with thyroid medications can increase your risk of imipramine side effects. If you are taking imipramine with thyroid medications, your healthcare provider may need to adjust your doses of these medications.
 
Tramadol
Combining imipramine pamoate with tramadol may increase the risk of serotonin syndrome. Check with your healthcare provider before taking these medications together.
 
Tricyclic Antidepressants
Taking imipramine with other tricyclic antidepressants can increase your risk of side effects. If you are taking imipramine with another tricyclic antidepressant, your healthcare provider may need to adjust your doses of these medications.
 
Triptans
Combining imipramine pamoate with a triptan may increase the risk of serotonin syndrome. Check with your healthcare provider before taking these medications together.
 
Tryptophan
Combining imipramine pamoate with tryptophan may increase the risk of serotonin syndrome. Check with your healthcare provider before taking these medications together.
 

Final Thoughts on Drug Interactions With Imipramine Pamoate

It is possible that not every imipramine drug interaction was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific drug interactions with imipramine that may apply to you.
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