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Drug Interactions With Imipramine Pamoate

Some of the medications that may potentially cause imipramine pamoate drug interactions include other tricyclic antidepressants, methylphenidate, blood pressure medicines, and barbiturates. Drug interactions with imipramine pamoate can alter the levels of some medicines in your blood or cause side effects. Make sure to talk with your healthcare provider or pharmacist about the imipramine pamoate drug interactions that may apply to you.

 

Drug Interactions With Imipramine Pamoate: An Introduction

 Imipramine pamoate (Tofranil PM®) can potentially interact with many other medicines. Some of the medicines that may lead to imipramine interactions include:
 
  • Alcohol
     
  • Anticholinergic medications, including:

 

 

  • Arrhythmia medications, including:

 

    • Amiodarone (Cordarone®)
    • Disopyramide (Norpace®)
    • Dofetilide (Tikosyn®)
    • Flecainide (Tambocor®)
    • Ibutilide (Corvert®)
    • Propafenone (Rythmol®)
    • Quinidine
    • Sotalol (Betapace®)

 

  • Barbiturates, including:

 

    • Amobarbital (Amytal®)
    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Secobarbital (Seconal®)

 

 

 

  • Phenothiazine medications, including:

 

 

 

    • Dopamine (Intropin®)
    • Dobutamine (Dobutrex®)
    • Epinephrine (Adrenalin®, EpiPen®)
    • Norepinephrine (Levophed®)

 

 

 

  • Thyroid medications, including:

 

 

 

 

(Drug Interactions With Imipramine Pamoate Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;