Depression
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Isocarboxazid (Cont.)

Alternatives to Isocarboxazid

Depression, even in its most severe form, is highly treatable. As with many illnesses, getting depression treatment early is more effective and reduces the chance of recurrence.
 
The most common forms of treatment for depression are medication (antidepressants) and psychotherapy ("talk therapy"). In some cases of severe depression, healthcare providers may recommend electroconvulsive therapy (ECT). Some people may also try complementary or alternative treatments for depression (see Natural Remedies for Depression).
 
Monoamine oxidase inhibitors, such as isocarboxazid, are usually used as a last resort, when other antidepressants have failed. Most people who take isocarboxazid will have tried most other alternatives to isocarboxazid for depression. These alternatives include:
 
  • Other monoamine oxidase inhibitors (MAOIs)
  • Selective serotonin reuptake inhibitors (SSRIs)
  • Serotonin-norepinephrine reuptake inhibitors (SNRIs)
  • Norepinephrine and dopamine reuptake inhibitors (NDRIs)
  • Tricyclic antidepressants.
     
(Click Marplan Alternatives to learn more about alternatives for isocarboxazid. Click Dealing With Depression to learn other ways of managing depression.)
 

Overdose With Isocarboxazid

People who take too much isocarboxazid may have overdose symptoms that could include:
 
  • A rapid heart rate (tachycardia)
  • Low blood pressure (hypotension)
  • Coma
  • Seizures
  • Trouble breathing
  • Slow reflexes
  • Fever
  • Sweating
  • Loss of life.
     
If you happen to overdose on isocarboxazid, seek medical attention immediately.
 
(Click Marplan Overdose for more information.)
 
(Isocarboxazid Continued: Page 6)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;