Lexapro Drug Interactions

The following sections explain in detail the potentially negative interactions that can occur when Lexapro is combined with any of the drugs listed above. 

It is not recommended that you drink alcohol while taking Lexapro. Combining alcohol and Lexapro may cause unwanted side effects (see Alcohol and Lexapro).

 

Taking Lexapro and aspirin together can increase your risk of stomach bleeding. Talk with your healthcare provider before taking aspirin and Lexapro together.

 

Taking cimetidine and Lexapro together can increase the level of Lexapro in your blood, increasing your risk of side effects. Your healthcare provider may need to lower your Lexapro dose or may suggest an alternative to cimetidine.

 

Taking ketoconazole with Lexapro may decrease the level of ketoconazole in your blood, perhaps making it less effective. Your healthcare provider may need to increase your ketoconazole dose.

 

Taking Lexapro with linezolid can cause a group of symptoms called serotonin syndrome. These symptoms can include confusion, hallucinations, fast heartbeat, feeling faint, a fever, sweating, muscle spasms, difficulty walking, and diarrhea. Talk with your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any of the symptoms mentioned above, as serotonin syndrome can be very dangerous.

 

Taking Lexapro with lithium can cause a group of symptoms called serotonin syndrome. Talk with your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome (see above), as it can be very dangerous.