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Lexapro

Lexapro is a prescription drug commonly used for treating depression and generalized anxiety disorder. As part of a class of drugs called selective serotonin reuptake inhibitors, it works by helping to block the reuptake of a chemical in the brain called serotonin. The medicine is available in both tablet and liquid form, and is not approved for use in children. Common Lexapro side effects include nausea, insomnia, and headache.

 

What Is Lexapro?

Lexapro® (escitalopram oxalate) is a prescription antidepressant medication used to treat a few conditions of the brain.
 

Who Makes Lexapro?

Lexapro is manufactured by Forest Pharmaceuticals.
 

What Is It Used For?

Lexapro is licensed to treat the following conditions:
 
(Click What Is Lexapro Used For? for more information, including possible off-label uses.)
 

How Does Lexapro Work?

Lexapro is part of a class of drugs called selective serotonin reuptake inhibitors, or
 SSRIs for short. SSRIs act on a specific chemical within the brain known as serotonin. Serotonin is one of several chemicals used to send messages from one nerve cell to another.
 
As a message travels down a nerve, it causes the end of the cell to release serotonin. The serotonin enters the gap between the first nerve cell and the one next to it. When enough serotonin reaches the second nerve cell, it activates receptors on the cell, and the message continues on its way. The first cell then quickly absorbs any serotonin that remains in the gap between cells. This is called "reuptake."
 
Normally, this process works without any problems. But when the levels of serotonin become unbalanced, it can cause a variety of conditions, including depression. Lexapro helps to block the reuptake of serotonin so that more remains in the space between the brain's nerve cells. This gives the serotonin a better chance of activating the receptors on the next nerve cell.
 

Effects of Lexapro

Several clinical studies have shown Lexapro to be effective at treating depression and generalized anxiety disorder. Also, a long-term study has shown that it can help prevent depression relapse.
  

When and How to Take It

Suggestions on how and when to take Lexapro include the following:
 
  • Lexapro comes in both tablet and liquid form. It is taken by mouth, usually once a day.
     
  • If you experience drowsiness, try taking it before bedtime. If it causes insomnia, try taking it in the morning.
     
  • You can take the medication with or without food. If it bothers your stomach, try taking it with food.
     
  • Take the drug at the same time each day to maintain an even level in your blood.
     
  • For this medicine to work properly, it must be taken as prescribed. It will not work if you stop taking it.
      

Dosing Information

The dose of Lexapro your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • Your age
  • The medical condition being treated
  • Other medical conditions you may have
  • Other medications you may be taking.
     
As always, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
 
(Click Lexapro Dosage for more information.)
 

Side Effects of Lexapro

As with any medicine, side effects can occur. However, not everyone who takes this medicine will experience side effects. If side effects occur, they are often minor and either require no treatment or can easily be treated by you or your healthcare provider. Serious side effects are less common.
 
The most common side effects of Lexapro include:
 
(Click Lexapro Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
 
You can also read about specific side effects in the following eMedTV articles:
 
 

Drug Interactions

Lexapro can potentially interact with a number of medicines (see Lexapro Drug Interactions for more information).
  

What Should I Tell My Healthcare Provider Before Taking Lexapro?

Talk with your healthcare provider prior to taking Lexapro if you have:
 
 
Also, let your healthcare provider know if you:
 
 
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
(Click Lexapro Precautions and Warnings to learn more, including information on who should not take the drug.)
 

Alternatives

Depression, even in its most severe form, is highly treatable. As with many illnesses, getting depression treatment early is more effective and reduces the chance of recurrence.
 
The most common forms of treatment for depression are medication (antidepressants) and psychotherapy ("talk therapy"). In some cases of severe depression, healthcare providers may recommend electroconvulsive therapy (ECT). Some people may also try complementary or alternative treatments for depression (see Natural Remedies for Depression).
 
For most people, Lexapro is quite effective at treating depression. It is also generally well tolerated. However, side effects may occur or the medicine may not work as well as needed. In these cases, your healthcare provider may recommend an alternative medication. Some examples of substitute depression medications include:
 
 
(Click Lexapro Alternatives to learn more. Click Dealing With Depression to learn other ways of managing depression.)
 

What If I Overdose on Lexapro?

People who take too much Lexapro may have overdose signs and symptoms that could include:
 
  • Dizziness
  • Low blood pressure (hypotension)
  • Drowsiness
  • Insomnia
  • Nausea or vomiting
  • Rapid heart rate (tachycardia)
  • Irregular heart rhythm (arrhythmia)
  • Kidney failure (renal failure)
  • Seizures
  • Coma
  • Loss of life.
 
If you happen to overdose on this medication, seek immediate medical attention.
 
(Click Lexapro Overdose for more information.)
 

How Should It Be Stored?

Lexapro should be stored at room temperature, away from moisture and heat. Both the tablets and liquid should be kept in airtight containers. Keep this drug -- and all medications -- out of the reach of children.
 

What Should I Do If I Miss a Dose?

If you do not take your Lexapro as scheduled, take your missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose.
 

Strengths of Lexapro

Lexapro tablets are available in three strengths:
 
  • Lexapro 5 mg
  • Lexapro 10 mg
  • Lexapro 20 mg.
 
The liquid form of Lexapro is available in one strength: Lexapro® Oral Solution 5 mg per 5 mL (equal to 5 mg per teaspoonful).
 

Generic Lexapro

There is currently no generic Lexapro available (see Generic Lexapro for more information).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;