Depression Home > Amitriptyline Sexual Side Effects

Impotence and a decreased sex drive are among the sexual side effects that can occur with amitriptyline. How commonly these side effects occur in people taking amitriptyline has not been reported. Therefore, it can be difficult to determine if the sexual side effects are caused by another condition or by amitriptyline itself. If during treatment with amitriptyline, sexual side effects become bothersome, you should make sure to talk with your healthcare provider.

An Overview of Amitriptyline Sexual Side Effects

Amitriptyline hydrochloride (Elavil®) is a prescription medication that is used for the treatment of depression. It is part of a group of medications called tricyclic antidepressants. As with any medicine, there are possible side effects with amitriptyline. Some of these side effects can affect a person's sexual well-being. In the case of amitriptyline, there have been a few sexual side effects reported. How commonly they occurred, however, was not reported.

Sexual Side Effects With Amitriptyline

In clinical studies using amitriptyline to treat depression, the following sexual side effects were reported:
  • A decreased sex drive (libido).
  • Impotence. Impotence is usually defined as a total inability to achieve an erection, an inconsistent ability to do so, or a tendency to sustain only brief erections. Ultimately, impotence is the repeated inability to get or keep an erection firm enough for sexual intercourse. Impotence is also known as erectile dysfunction (or ED for short).

Amitriptyline, Sexual Side Effects, and Suggestions

It is impossible for your healthcare provider to know whether you will develop any sexual side effects while taking amitriptyline. Also, if a person does develop sexual side effects, it is difficult to know whether these problems are caused by another condition or amitriptyline itself.
However, if during treatment with amitriptyline, sexual side effects become a problem, you should be sure to talk with your healthcare provider. There are treatments that he or she may be able to recommend, such as an erectile dysfunction medication. Depending on the severity of your sexual side effects, he or she may also recommend that you adjust your amitriptyline dosage or try another medication for depression.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
Other Articles in This eMedTV Presentation

Topics & Medications


Related Channels

eMedTV Links
Copyright © 2006-2020 Clinaero, Inc.

eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.

This site complies with the HONcode standard for trustworthy health information:
verify here.