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Aplenzin Drug Interactions ExplainedThe following sections explain in detail the potentially negative interactions that can occur when Aplenzin is combined with any of the drugs listed above.
It is not recommended to drink alcohol while taking Aplenzin. Combining alcohol and this antidepressant may cause unwanted side effects. However, because stopping alcohol abruptly while taking Aplenzin can increase your risk of seizures, talk to your healthcare provider before you stop drinking alcohol.
Taking Aplenzin with other antidepressants may affect the level of Aplenzin and the other antidepressant in your blood, increasing your risk of side effects. Also, taking Aplenzin with other antidepressants may increase your risk of seizures. Talk with your healthcare provider before combining Aplenzin with other antidepressant medications.
You should not take Aplenzin along with other products containing bupropion, including Budeprion SR®, Budeprion XL®, Buproban®, Forfivo™ XL, Wellbutrin®, Wellbutrin SR®, Wellbutrin XL®, and Zyban®.
Taking Aplenzin and amantadine may increase your risk of side effects. Your healthcare provider may decide to start you at a lower Aplenzin dose if you are taking amantadine.
Aplenzin can increase the level of some antipsychotic medications in your blood, increasing your risk of side effects. Also, taking Aplenzin with antipsychotic medications may increase your chance of seizures. Talk with your healthcare provider before taking these medications together.
Aplenzin may increase the level of beta blockers in your blood, increasing your risk of side effects. Your healthcare provider may need to monitor you more closely and may need to decrease your dose of beta blockers.