Depression Home > Deplin Uses
If you have depression or schizophrenia, a healthcare provider may prescribe Deplin. Using this vitamin in combination with antidepressants and antipsychotics can help improve the effectiveness of the medications. Because it contains the active form of folic acid, Deplin can increase certain brain chemicals that become low in people with depression and decrease certain amino acids that become elevated in people with schizophrenia.
What Is Deplin Used For?Deplin® is a prescription vitamin that contains L-methylfolate, which is the active form of folate in the body. It is approved for use as a nutritional supplement in people with:
- Major depressive disorder who have low folate levels
- Schizophrenia who have, or are at risk for, high blood levels of homocysteine (medically called hyperhomocysteinemia).
Using Deplin for Major Depressive DisorderMajor depressive disorder, sometimes called major depression or clinical depression, is a serious illness. It is not the same thing as a passing low mood, or feeling sad or down in the dumps. Major depression interferes with a person's ability to function by affecting their mood, thoughts, and physical health. Oftentimes, people with major depression find it difficult to do the things they normally did before they were depressed.
- A persistent sad, anxious, or "empty" mood
- Feelings of hopelessness and pessimism
- Feelings of guilt, worthlessness, and helplessness
- Loss of interest or pleasure in activities that used to be enjoyable
- Low energy or fatigue
- Problems concentrating
- Changes in sleep
- Changes in appetite
- Feeling irritable or restless
- Thoughts of death or suicide
- Physical symptoms, such as headaches or pain.