Depression Home > Deplin Warnings and Precautions
Make sure to let your healthcare provider know if you have anemia, a seizure disorder, or bipolar disorder before starting treatment with Deplin. Other precautions and warnings with this prescription vitamin involve the risk of potential drug interactions and allergic reactions. Also, you may not be able to take Deplin if you are pregnant or breastfeeding.
What Should I Tell My Healthcare Provider?You should talk with your healthcare provider prior to taking Deplin® if you have:
- Low blood levels of vitamin B12
- Bipolar disorder
- A seizure disorder
- Tumors or cancer of the colon
- Any allergies, including to foods, dyes, or preservatives.
- Pregnant or thinking of becoming pregnant
Specific Precautions and Warnings With DeplinSome warnings and precautions to be aware of prior to taking this vitamin include the following:
- Deplin contains a form of folic acid, which can mask anemia due to vitamin B12 deficiency. This means it will be more difficult to determine if you have B12 deficiency while you are taking Deplin. Your healthcare provider may test you for this type of anemia before you start taking Deplin.
- High doses of folic acid may increase the risk for seizures in people with seizure disorders. Deplin contains a form of folic acid. Therefore, let your healthcare provider know if you have a seizure disorder before you take this supplement.
- Treating depression with antidepressants in people with bipolar disorder may increase the risk for mania (an excessive elevation in mood). Although Deplin is not an antidepressant, it can increase the effects of antidepressants. Make sure your healthcare provider knows your complete mental health history before you start taking Deplin.
- Large doses of folic acid may accelerate the growth of colon tumors. It is unknown if Deplin, which contains an active form of folic acid, has the same effect on colon tumors. If you have cancer of the colon, talk to your healthcare provider before taking Deplin.
- Deplin may react with a number of other medicines (see Deplin Drug Interactions).
- It is unknown if Deplin is safe for pregnant women. Talk to your healthcare provider about the risks and benefits of using Deplin during pregnancy (see Deplin and Pregnancy).
- It is unknown if Deplin passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider before taking the drug (see Deplin and Breastfeeding).