Depression Home > Precautions and Warnings With Desipramine
Some precautions and warnings with desipramine include possible drug interactions, the safety of taking desipramine while pregnant, and the risk of withdrawal symptoms or a dry mouth in some people taking this medicine. Among the people who should not take desipramine are those who have recently had a heart attack and those who are taking monoamine oxidase inhibitors (MAOIs). A few of the conditions that you should let your healthcare provider know about before you take desipramine include glaucoma, seizures, and heart problems (including heart disease).
You should talk with your healthcare provider prior to taking desipramine hydrochloride (Norpramin®) if you have:
- Bipolar disorder (manic depression) or a family history of bipolar disorder
- A history of suicide attempts or suicidal thoughts
- Severe anxiety or agitation
- A recent history of a heart attack
- Heart problems, including heart disease
- Hyperthyroidism (overactive thyroid)
- Bladder problems or difficulty passing urine
- An enlarged prostate (also known as benign prostatic hyperplasia or BPH)
- Any allergies, including allergies to foods, dyes, or preservatives.
Also let your healthcare provider know if you:
- Are pregnant or thinking of becoming pregnant
- Are breastfeeding
- Drink alcohol regularly.
You should also make sure to tell your healthcare provider about all other medicines you may be taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.