Depression Home > Lexapro Drug Interactions

Lexapro and Serotonin Syndrome

Several of the known interactions with Lexapro are related to a potentially dangerous group of symptoms known as serotonin syndrome. Such symptoms might include:
 
  • Confusion
  • Hallucination
  • Fast heartbeat
  • Feeling faint
  • Fever
  • Sweating
  • Muscle spasm
  • Difficulty walking
  • Diarrhea.
 
Serotonin syndrome usually occurs when people take more than one medication that affects serotonin at the same time. Talk to your healthcare provider before taking these medications together. In many cases, such combinations are still recommended, although with more careful monitoring. Call your healthcare provider right away if you have any of these symptoms, as serotonin syndrome can be dangerous.
 

Lexapro Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Lexapro is combined with any of the drugs listed above. 

 

Alcohol
It is not recommended that you drink alcohol while taking Lexapro. Combining alcohol and Lexapro may cause unwanted side effects (see Alcohol and Lexapro).
 
Aspirin
Taking Lexapro and aspirin together can increase your risk of stomach bleeding. Talk with your healthcare provider before taking aspirin and Lexapro together.
 
Buspirone (BuSpar)
Because combining Lexapro with buspirone may increase the risk of serotonin syndrome, check with your healthcare provider before taking these medications together.
 
Cimetidine (Tagamet)
Taking cimetidine and Lexapro together can increase the level of Lexapro in your blood, increasing your risk of side effects. Your healthcare provider may need to lower your Lexapro dose or may suggest an alternative to cimetidine.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
Other Articles in This eMedTV Presentation
Advertisement


Topics & Medications

Quicklinks

Related Channels

eMedTV Links
Copyright © 2006-2019 Clinaero, Inc.

eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.

This site complies with the HONcode standard for trustworthy health information:
verify here.