Nortriptyline hydrochloride (Pamelor®) is approved for the treatment of major depression in adults. It is believed to work by affecting the levels of certain chemicals in the brain, allowing more to remain, thereby relieving symptoms of depression. It comes in the form of capsules, and nortriptyline is generally taken anywhere from one to four times a day.
Most people don't experience any problems when taking nortriptyline capsules; however, a liquid form is also available for those who have difficulty swallowing the capsules. In addition, you may find that taking this medication with food helps prevent stomach upset. If you experience drowsiness or dizziness during treatment, ask your healthcare provider if you can take nortriptyline before bedtime to help avoid this.
(Click Nortriptyline to learn more about this antidepressant, including exactly how it works, how long it takes for the effects to be felt, possible side effects, and what to do if you take too much.)
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: Approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed February 20, 2007.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 7th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2005.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed February 20, 2007.
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