Depression Home > Oleptro Drug Interactions

When antiplatelet medications, nonsteroidal anti-inflammatory drugs, or monoamine oxidase inhibitors are taken with Oleptro, drug interactions may occur. These interactions can alter the level of Oleptro in your blood and increase your risk of side effects. Notify your healthcare provider immediately if you develop symptoms such as hallucinations, fever, or difficulty walking while taking this medication.

An Overview of Interactions With Oleptro

Oleptro™ (trazodone ER) can potentially interact with a number of other medications. Some of the medicines that may lead to drug interactions with Oleptro include but are not limited to:
  • Medications that "thin" the blood (such as anticoagulant and antiplatelet drugs), such as:
      • Alteplase (Activase®)
      • Reteplase (Retavase®)
      • Streptokinase (Streptase®)
      • Tenecteplase (TNKase®)


Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
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