Although Paxil® and Pexeva are similar medications, they are chemically different. Both medications contain the active ingredient paroxetine. However, Paxil contains paroxetine hydrochloride, while Pexeva contains paroxetine mesylate.
Both forms of paroxetine (hydrochloride and mesylate) are equivalent, which means they should be expected to have the same actions in the body. However, they are technically not interchangeable -- this means your pharmacist cannot switch you from one form to the other without a new prescription from your healthcare provider.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed October 19, 2010.
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