Clinical studies have shown Pristiq® (desvenlafaxine succinate) to be effective for depression treatment in adults. These studies also showed that a lower Pristiq dosage (50 mg per day) is just as effective and causes fewer side effects, compared to a higher dose (100 mg per day).
Pristiq is part of a group of medications called serotonin-norepinephrine reuptake inhibitors, or SNRIs for short. SNRIs act on specific chemicals within the brain known as serotonin and norepinephrine. When the levels of these chemicals become unbalanced, it can cause conditions such as depression. Pristiq helps block the reuptake of serotonin and norepinephrine so that more remains in the space between the brain's nerve cells.
(For more details on this drug and its effects, click Pristiq. This article offers a complete overview of this medication, with information on dosing guidelines, safety issues to discuss with your healthcare provider, and more.)
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Pristiq [package insert]. New York, NY: Pfizer Inc;2012 December.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed April 4, 2008.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed March 11, 2008.
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