Depression Home > Prozac Side Effects
Insomnia, weakness, and loss of appetite are among the most common side effects reported with Prozac. Some of the side effects that are rare (seen in less than 1 percent of patients) include canker sores, high cholesterol, and acne. In most cases, side effects of Prozac are minor and either do not require medical attention or can be treated easily. However, if you develop any serious problems, such as suicidal thoughts or behavior, hallucinations, or panic attacks, notify your healthcare provider immediately.
As with any medicine, there are possible side effects with Prozac® (fluoxetine hydrochloride). However, not everyone who takes the antidepressant will have problems. In fact, most people tolerate the drug well. When Prozac side effects do occur, in most cases they are minor and either require no treatment or can easily be treated by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Prozac. Your healthcare provider can discuss a more complete list of Prozac side effects with you.)
Prozac has been studied thoroughly in clinical trials in which the side effects seen with a group of people taking the drug are documented and compared to another group not taking the medicine. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.
In clinical studies, the most common side effects of Prozac included:
- Insomnia -- in up to 33 of people (see Prozac and Insomnia)
- Nausea -- up to 29 percent
- Weakness -- up to 21 percent
- Headache -- up to 21 percent
- Diarrhea -- up to 18 percent
- Loss of appetite -- up to 17 percent (see Prozac and Weight Loss)
- Drowsiness -- up to 17 percent
- Anxiety -- up to 15 percent
- Nervousness -- up to 14 percent
- Shakiness (tremor) -- up to 13 percent
- Dry mouth -- up to 12 percent (see Prozac and Dry Mouth)
- Decreased sex drive -- up to 11 percent (see Prozac Sexual Side Effects)
- Yawning -- up to 11 percent
- Indigestion -- up to 10 percent
- Dizziness -- up to 9 percent
- Sweating -- up to 8 percent
- Impotence -- up to 7 percent (see Prozac Sexual Side Effects)
- Ejaculation problems -- up to 7 percent (see Fluoxetine and Premature Ejaculation).
Other common Prozac side effects (that occurred in at least 1 percent of people) include:
- Flushing (redness of the skin, especially the face)
- Abnormal dreams
- Fever or chills
- Weight loss (see Prozac and Weight Loss)
- Vision changes
- Chest pain
- High blood pressure (hypertension)
- Increased appetite and weight gain (see Prozac and Weight Gain)
- Taste changes.