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Clinical studies on Remeron and suicide showed that there is an increased risk of suicidal thoughts or behaviors in children and teenagers who took this or other antidepressants. While Remeron has not been approved for use in children and teenagers, it may be prescribed for off-label use. Therefore, if you or your child is taking Remeron and you notice suicidal thoughts or behaviors, contact your healthcare provider.
Remeron and Suicide: An OverviewRemeron® (mirtazapine) is a prescription medication used for the treatment of depression in adults. As with all antidepressants, there may be an increased risk of suicidal behavior when taking it.
The FDA's Warning on Remeron and SuicideThe U.S. Food and Drug Administration (FDA) has issued a special warning about the risk of suicidal thoughts and behavior with antidepressant use in children and teenagers. The warning was issued due to concerns that antidepressants seemed to increase the risk of such behavior in children and teenagers in clinical studies.
Although Remeron is not approved for use in children and teens, it may be used in an "off-label" fashion for these age groups.
Does Remeron Cause Suicide?In clinical studies, it did appear that there was a slightly increased risk of suicidal behavior in children and teenagers who took antidepressants, including Remeron. In one study, about 4 percent of children and teens taking an antidepressant had suicidal thoughts or behavior, compared to 2 percent of children and teens who were not taking an antidepressant. This study looked at all suicidal behavior, including suicides, attempted suicides, and thoughts about committing suicide. It is important to note that no one in the study actually committed suicide.
It is difficult to know for sure if antidepressants cause suicidal behavior. To make matters more confusing, depression itself can cause suicidal behavior. The bottom line is that you should report any signs of suicidal behavior to your healthcare professional, whether you are taking an antidepressant or not.
Certain people seem to be at a higher risk for suicidal behavior while taking antidepressants. This includes people with bipolar disorder (or a family history of the condition) and people who have attempted suicide (or who have a family history of suicide attempts).