Depression Home > Comparisons of SSRI Antidepressants

Other Important SSRI Comparisons

All SSRIs (except Paxil and Paxil CR) are classified as pregnancy Category C medications, meaning that they may not be safe for use during pregnancy (although in some situations, the benefits may outweigh the risks). Pexeva, Paxil, Paxil CR, and Brisdelle, however, are pregnancy Category D medications, meaning that they have been shown to cause harm to the fetus and generally should not be used during pregnancy. This is due to certain birth defects that paroxetine may cause (see SSRIs and Pregnancy for more information).
In general, SSRIs usually have similar side effects (see SSRI Side Effects). While all SSRIs can cause withdrawal symptoms if stopped abruptly, it seems that Prozac is least likely to cause withdrawal symptoms because it stays in the body for such a long time (see SSRI Withdrawal).
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Last reviewed by: Kristi Monson, PharmD;
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