Depression Home > Tofranil Warnings and Precautions

Who Should Not Take Tofranil?

You should not take Tofranil if you:
  • Are allergic to Tofranil, imipramine hydrochloride, or any inactive component used to make Tofranil. Your healthcare provider or pharmacist has a list of the inactive ingredients.
  • Have recently had a heart attack (known medically as a myocardial infarction).
  • Are taking linezolid (Zyvox®) or intravenous methylene blue. Tofranil should not be started in people taking linezolid or IV methylene blue, but a person already taking Tofranil may be given linezolid or methylene blue, if absolutely necessary, and only with very careful monitoring and only if Tofranil is stopped during treatment.
  • Have used a monoamine oxidase inhibitor (MAOI) within the last 14 days. MAOIs include:

Tofranil Warnings and Precautions: Final Thoughts

There are a number of situations in which Tofranil should not be taken, as well as several precautions and warnings people should be aware of before starting the drug. However, it is possible that not all precautions or warnings were discussed in this article. Therefore, you should talk with your healthcare provider about the specific Tofranil warnings and precautions that may apply to you.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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