Depression Home > Precautions and Warnings With Trazodone

Who Should Not Take Trazodone?

You should not take trazodone if you:
  • Are allergic to Desyrel, trazodone, or any of the inactive components used to make the medicine. Your healthcare provider or pharmacist has a list of the inactive ingredients.
  • Are taking linezolid (Zyvox®) or intravenous methylene blue. Trazodone should not be started in people taking linezolid or IV methylene blue, but a person already taking trazodone may be given linezolid or methylene blue, if absolutely necessary, and only with very careful monitoring and only if trazodone is stopped during treatment.
  • Have taken a monoamine oxidase inhibitor (MAOI) within the past two weeks. MAOIs include:

Final Thoughts on Precautions and Warnings With Trazodone

There are a number of situations in which trazodone should not be taken, as well as several precautions and warnings people should be aware of before beginning treatment. However, it is possible that not all warnings and precautions were discussed in this article. Therefore, you should talk with your healthcare provider about any specific precautions and warnings with trazodone that may apply to you.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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