Is there a link between tricyclic antidepressants and suicide? In clinical studies, there appeared to be an increased risk of suicidal thoughts and behavior in children and teenagers who took antidepressants (including tricyclic antidepressants). Although tricyclic antidepressants have not been approved for use in children and teenagers with depression, they can be prescribed off-label to treat other conditions for these age groups.
An Overview of Tricyclic Antidepressants and Suicide
Tricyclic Antidepressants and Suicide: FDA Warning
The U.S. Food and Drug Administration (FDA) has issued a special warning about the risk of suicidal thoughts and behavior with antidepressant use in children and teenagers. The warning was issued due to concerns that antidepressants seemed to increase the risk of suicidal behavior in children and teenagers in clinical studies.
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